I'm no specialist but do you feel like you would want/need the extra speed that comes with RAID 10. Basically, RAID6 will be slower but can handle 2 failures. RAID10 is faster with the 0 in there but can only handle "1.5" failures.
FWIW, in a similar situation, we went with 10 because of the want for extra speed. We also had 3-4 extra HDDs on the shelf next to the server to hot swap in, in case of failure.