Rabid organ transplant kills Maryland man

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bononos

Diamond Member
Aug 21, 2011
3,911
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OK I admit I'm not a doctor, but wouldn't you test an organ for practically EVERYTHING before giving it to someone else?
I don't think it weighs heavily on the ghouls who grab diseased bodyparts. Its a relatively unregulated trade and the industry wants to keep it that way.
 

lxskllr

No Lifer
Nov 30, 2004
58,014
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I think there's been a case report of someone incubating rabies for several decades, but I thought that nerves were the only reservoir in the body.

Lovely. I got bitten by a cat a couple years ago that I was trying to remove from a friend's basement. I assumed it was because she was pregnant, but it was probably rabid. Well, that explains my posts. NOT MT FAULT!
 

CottonRabbit

Golden Member
Apr 28, 2005
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~10,000 kidney transplants from deceased donors are done each year in the US. There are less than a handful of cases of rabies each year.
 

Mr. Pedantic

Diamond Member
Feb 14, 2010
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Lovely. I got bitten by a cat a couple years ago that I was trying to remove from a friend's basement. I assumed it was because she was pregnant, but it was probably rabid. Well, that explains my posts. NOT MT FAULT!

You're probably alright. Most rabies cases have an incubation of a few weeks to months.

It's interesting the types of diseases that cats transmit though.
 

ichy

Diamond Member
Oct 5, 2006
6,940
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I don't think it weighs heavily on the ghouls who grab diseased bodyparts. Its a relatively unregulated trade and the industry wants to keep it that way.

I hope that someday you need an organ transplant. Idiot.
 

ichy

Diamond Member
Oct 5, 2006
6,940
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~10,000 kidney transplants from deceased donors are done each year in the US. There are less than a handful of cases of rabies each year.

I was going to say, rabies in humans is so incredibly rare in the US that the delay that would come with testing organs would probably do more harm than good. When you've got a potential organ donor it's a use it or lose it situation.
 

shortylickens

No Lifer
Jul 15, 2003
80,287
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On an unrelated topic I think if you get a nasty disease you should take yourself off the donor list. Thats just common courtesy.
 

Mr. Pedantic

Diamond Member
Feb 14, 2010
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On an unrelated topic I think if you get a nasty disease you should take yourself off the donor list. Thats just common courtesy.

Even if you don't know that you got a nasty disease? Like CJD, or, as is the case with a lot of people who got transfusions in the 80s and 90s, HCV?
 

shortylickens

No Lifer
Jul 15, 2003
80,287
17,079
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Even if you don't know that you got a nasty disease? Like CJD, or, as is the case with a lot of people who got transfusions in the 80s and 90s, HCV?

If you get bit you need to a see a doctor to check for rabies. If you go to the hospital they should do that anyways.

This situation was a colossal failure on the part of many people.
 

JoeyM

Senior member
Nov 18, 2003
362
6
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How can they treat the other organ recipients for rabies? Aren't they immunosuppressed to keep them from rejecting the organ? Will vaccinations and a single dose of antibodies (immunoglobulin) work on somebody taking all those medications to prevent immune response?

Joe
 

Mr. Pedantic

Diamond Member
Feb 14, 2010
5,027
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If you get bit you need to a see a doctor to check for rabies. If you go to the hospital they should do that anyways.

This situation was a colossal failure on the part of many people.
What if you can't afford it?

How can they treat the other organ recipients for rabies? Aren't they immunosuppressed to keep them from rejecting the organ? Will vaccinations and a single dose of antibodies (immunoglobulin) work on somebody taking all those medications to prevent immune response?

Joe
You're not that immunosuppressed. At first after transplant the immunosuppression is pretty high, but as time goes on you can get it down. Usually for kidney transplants you can get it down to just tacrolimus/cyclosporin, which inhibits T-cells, but it doesn't really do anything against B-cells.
 

Gibsons

Lifer
Aug 14, 2001
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What if you can't afford it?


You're not that immunosuppressed. At first after transplant the immunosuppression is pretty high, but as time goes on you can get it down. Usually for kidney transplants you can get it down to just tacrolimus/cyclosporin, which inhibits T-cells, but it doesn't really do anything against B-cells.

This, plus the rabies vaccine is safe to give to immunosuppresed patients. You should expect a higher failure rate, but there's no reason you can't just dose them twice.

Also, I think there are passive immunizations available for rabies, that should work pretty well also.
 

Fritzo

Lifer
Jan 3, 2001
41,914
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OK...OK...I found what happened. Doctors have sloppy handwriting, and the surgery sheet said "PATIENT REQUIRES *RAPID* KIDNEY TRANSPLANT".
 

sourn

Senior member
Dec 26, 2012
577
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If you get bit you need to a see a doctor to check for rabies. If you go to the hospital they should do that anyways.

This situation was a colossal failure on the part of many people.

LOL what a panzy.

If I get bit by an animal I'm not gonna run screaming and crying to the doctor like a little bitch. Well unless of course it's foaming at the mouth.
 

Gibsons

Lifer
Aug 14, 2001
12,530
35
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LOL what a panzy.

If I get bit by an animal I'm not gonna run screaming and crying to the doctor like a little bitch. Well unless of course it's foaming at the mouth.

A lot depends on what animal it is. If it's a bat, I'm getting a rabies shot, every time.
 

Mr. Pedantic

Diamond Member
Feb 14, 2010
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LOL what a panzy.

If I get bit by an animal I'm not gonna run screaming and crying to the doctor like a little bitch. Well unless of course it's foaming at the mouth.

As Gibs said, if it's a bat, you assume it had rabies until proven otherwise.