I schedule mine to quick scan daily and full scan weekly. Basically a quick scan looks in common places for viruses/spyware and a full scan is everywhere.
I'm not sure why you all scan so much. It's much better to have a proactive security strategy rather than a reactive one. Scan downloads before you run them, use a limited user account, keep your OS and programs updated, use an anti-executable type (SRP, HIPS, Behavior Blocker) program. You can even try a sandbox or light virtualization applications.
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