There's a couple of reasons why it might not. I installed it yesterday and before I used the installation CD I got a message from Windows saying that since I had installed new hardware, it made some changes that required a reboot, so I rebooted, and got a Blue Screen. After a few hours with Microsoft (they only made matters worse, I decided to clean out the box, get the dust out and reinstall the old driver. That works now, but I'm not sure if the blue screen was caused by the new card, or just some stupid windows issue.
And the reason I got this card is so that, for my next upgrade, I can get a new mobo. I upgrade one piece at a time.