Is this possible, somehow, on universal level?
I started Prime95 on wife's PC, and walked away. When I came back, I realized the damn thing went to sleep, and two hours were wasted. What shall I do, except for disabling sleep completely, which I don't want to.
The issue is that your program isn't setting the proper flag to suspend sleep mode. For example, if you start a movie in WMP and don't touch anything the computer will play it to conclusion without sleeping.
Since P95 doesn't have that feature, you'll have to either alter your sleep setting or use a program to subvert the sleep cycle like Mouse Jigger as posted.
Since P95 is just stability testing, I'd suggest changing your power setting for the duration of testing and then go back to your normal profile.