Some possibilities come to mind:
1. Something that draws a lot of current is drawing the line down close to the point where the regulation of audio gear's power supply is marginal. Examples include a refrigerator, air conditioner, etc.
If you have an AC volt meter, measure the line voltage. It should be close to 117 volts AC.
Try unplugging other items on the same cicuit and/or try plugging the audio gear into another socket.
2. Some other electronic device is generating air or line borne interference, possibly in the RF band, that is interacting with the audio electronics. Examples would be a cell phone or cordless phone. For example, if it's a cordless phone, try moving the phone's base station to another point in the room.
3. Check your grounding. The shield in some cheap audio cables with RCA connectors can become damaged, especially at the connectors.
Try unplugging all analog sources. If the problem disappears, try re-connecting them one at a time until the problem returns. If that finds it, try new RCA cables.
If you have a phonograph turntable with a magnetic cartridge, it could be an easy point to introduce interference.
4. Again on the subject of grounding, if any of your audio components have two prong AC plugs, you may have to turn one of them over. Sometimes, you can actually feel an electric tingle when lightly running your finger over the metal surfaces of two piece of gear.
5. Yet again on the subject of grounding, are the ground lugs of your AC wall connectors connected to house ground? Some older installations have three wire plugs with only the two flat contacts connected.
If the ground lugs are all connected, are they properly returned to ground at the AC mains?
Hope that helps.