Depends on your use really...
If you are a graphic artist sure, though in my personal opinion, I prefer NEC's professional line better than Samsung's for imaging work.
If you are going in for gaming, then sure, you might be able to tell the difference. This is really a subjective thing though. It all depends on how good your eyes are. I would suggest comparing two side-by-side if possible. Personally, I don't see much difference between the two... And if you are considering gaming, then video card may indeed a factor, as even two 8800 Ultra's in SLI can't run every game maxed out at those resolutions.
It really all just depends on your intended use...