I play with a HD7770, which is I believe a bit weaker than a 750. It struggles with newer games, but I have played every game I tried at 1080p usually medium to high, but low on really demanding titles. The only game I have been unable to get over 30FPS is witcher 3. Even played that on my second monitor 1440 x 900 and it still didnt break 30FPS. But I am not one of those who demands really high framerates, so I did finish the game.
Honestly, instead of ushering in a new age of PC gaming, I think the consoles being x86 have actually led to even more lazy porting to the PC, especially the excessive vram requirements in relation to the visual quality. But really there are no new games out that I want to play bad enough to upgrade. I played DA:I and W3 on my 7770, and despite the high system requirements, I think it will handle FO4. Otherwise, I will just stick with older games.