I'm assuming you mean P4 optimizations. Yes, there are certain P4 optimizations out there. SSE, SSE2, SSE3, and HT support all favor the P4 over any AMD chip. The reason why SSE and SSE 2 help the P4 more than an Athlon is because the P4 runs at a higher clock speed and does more SSE/SSE2 instructions per second. SSE and HT helps the P4 because no Athlon has them (yet). Along with this, certain types of tasks favor the P4 because of it's design. The classic example is content creation. The P4 design favors a constant stream of data (more so than AMD's chips), and content creation provides this. The reason for this is that ever time the has to guess about the next instruction, the P4 has a much more dramitic hit on performance than AMD's chips. In addition, content creation apps often make good use of SSE/SSE2 instructions, helping the P4 even more.
To understand more about how certain optimizatoins favor different processors, you need to have a good understand how each processor differs from the others.