If you switched the settings in the BIOS for your RAM to run at 133 u'd get a performance increase with PC133 yup.. but it's negligible when there are other things maybe u could upgrade for a more useful reason.. such as a video card, or something. you probably wouldn't notice a hell of alot of difference at 133 as you would with a faster video card. but if you've already got a good video card and u just want to buy some PC133. sure why not. Sandra will show a slight improvement....