On that board the memory setting is how many times faster than the FSB the memory runs. Selecting 2.00 will give you what is normally referred to as a 1:1 ratio. (So at stock, with your E2180's 200MHz FSB, your memory will be running at DDR2-400.)
For now leave it on 2.0 while you overclock your CPU. Once you've achieved your desired CPU overclock, then worry about ratcheting up the RAM speed if you care to. Personally, I'd just leave it running 1:1 anyway.