NON_POLITICAL China Coronavirus THREAD

[K1052]

Let's hope for more than 1 yr. Time will tell.

The Johnson and Johnson vaccine in the pipeline is a one shot that currently shows more antibodies produced than 2 shot ones and requires nothing more than regular refrigeration. Sounds promising.

Johnson & Johnson's one-shot COVID-19 vaccine grants promising response in early study

In an early safety study, Johnson & Johnson's one-shot COVID-19 vaccine produced immune proteins in more than 90% of participants.

www.latimes.com

Phase 2 data looks good. Hopefully the phase 3 will be released in a week or two. As long as it all works the more the merrier.

 

[K1052]

Uh wut?

https://twitter.com/i/web/status/1350097480642424836

 

[CZroe]

Uh wut?

https://twitter.com/i/web/status/1350097480642424836

What happened to the "millions" of doses supposedly waiting at Pfizer for instructions for someplace to ship to/take delivery? If all have been distributed then why don't we have 40 million vaccinations out there already?

 

[K1052]

What happened to the "millions" of doses supposedly waiting at Pfizer for instructions for someplace to ship to/take delivery? If all have been distributed then why don't we have 40 million vaccinations out there already?

Azar appears unable to tell us truthfully what is going on or simply does not know. Either one isn't good.

 

[Ajay]

Geez, 30M doses distributed, 11M administered. Sad.

COVID Data Tracker

CDC’s home for COVID-19 data. Visualizations, graphs, and data in one easy-to-use website.

covid.cdc.gov

 

[local]

Oh joy! Good long term but people don't see things that way.

EU states warn of risks to vaccination credibility as Pfizer slows supplies

European governments said the credibility of their COVID-19 vaccination programmes was at risk on Friday after U.S. pharmaceutical firm Pfizer announced a temporary slowdown of deliveries of its vaccines.

www.reuters.com

 

[K1052]

Given the shambles that a lot of states/counties are in trying to do this it seems like a good move.

https://twitter.com/i/web/status/1350183143031119877

 

[Svnla]

New strain could spike up new cases of virus infection.

C.D.C. Warns the New Virus Variant Could Fuel Huge Spikes in Covid-19 Cases

The more contagious version, first identified in Britain, is expected to spread widely and lead to further strains on an already overburdened health care system.

www.nytimes.com

.

 

[local]

Pfizer is unblinding all of Phase 3 and I can now get in line now. I am considered essential by the Texas gov but so is everyone else so I assume I will be the last person in Texas to get the vaccine.

 

[Svnla]

Multiple deaths in Norway from the vaccine from Pfizer. Mostly from the elders.

Norway Raises Concern Over Vaccine Jabs for the Elderly

Norway expressed increasing concern about the safety of the Pfizer Inc. vaccine on elderly people with serious underlying health conditions after raising an estimate of the number who died after receiving inoculations to 29.

www.bloomberg.com

 

[Ichinisan]

Blood plasma treatment is ineffective.

 

[Ichinisan]

Multiple deaths in Norway from the vaccine from Pfizer. Mostly from the elders.

Norway Raises Concern Over Vaccine Jabs for the Elderly

Norway expressed increasing concern about the safety of the Pfizer Inc. vaccine on elderly people with serious underlying health conditions after raising an estimate of the number who died after receiving inoculations to 29.

www.bloomberg.com

I haven't read it yet. Considering that these people are elderly / vulnerable / at-risk, is it likely many of these deaths are unrelated to any vaccine?

 

[s0me0nesmind1]

J&J phase 2 data looks promising

https://twitter.com/i/web/status/1349490555462553606

I don't keep up with this stuff... at all... but can you summarize up for me why big-notch companies such as J&J (and others I presume) took so much longer than Pfizer / Moderna?

 

[s0me0nesmind1]

I haven't read it yet. Considering that these people are elderly / vulnerable / at-risk, is it likely many of these deaths are unrelated to any vaccine?

Isn't a vaccine just a weakened form of the virus?

At what point (when you already have a compromised immune system) does it not seem.... possible, that a vaccine could have more negatives for SOME VERY VERY FEW people?

No, I'm not suggesting anti-vax shit here - just asking a question.

 

[Svnla]

I haven't read it yet. Considering that these people are elderly / vulnerable / at-risk, is it likely many of these deaths are unrelated to any vaccine?

Well, right now they are investigating the root cause(s). Can't say for sure the vaccine was the main reason to push those elders over the edge.

Maybe those elders had reactions to the vaccine and their frail health couldn't handle them as more healthy folks would?

 

[Ichinisan]

Isn't a vaccine just a weakened form of the virus?

At what point (when you already have a compromised immune system) does it not seem.... possible, that a vaccine could have more negatives for SOME VERY VERY FEW people?

No, I'm not suggesting anti-vax shit here - just asking a question.

These mRNA vaccines are new and different. It's certainly possible that people have bad reactions to the vaccine (allergic or otherwise). I'm merely hopeful that the bad numbers could have an alternate explanation.

Anyway, I don't know if "weakened" is really the right word for a traditional vaccine, but I have heard that many times. If I understand correctly, I think it's supposed to be unable to reproduce in your body.

 

[Ichinisan]

I don't keep up with this stuff... at all... but can you summarize up for me why big-notch companies such as J&J (and others I presume) took so much longer than Pfizer / Moderna?

If I understand correctly, the mRNA vaccines were developed based on the published genome - before a single case was confirmed in USA. The first one was developed before the scientists had any sample of the actual virus. It's some serious science.

That said, it's possible the virus was already spreading here. We weren't able to start testing for a while.

 

[ch33zw1z]

Multiple deaths in Norway from the vaccine from Pfizer. Mostly from the elders.

Norway Raises Concern Over Vaccine Jabs for the Elderly

Norway expressed increasing concern about the safety of the Pfizer Inc. vaccine on elderly people with serious underlying health conditions after raising an estimate of the number who died after receiving inoculations to 29.

www.bloomberg.com

The deaths, according to that article, is all in the elders area with serious underlying conditions. 13 being confirmed, 16 pending investigation. New confirmed lower the age range from 80 to 75. The article reports more than 42,000 doses given.

 

[K1052]

I don't keep up with this stuff... at all... but can you summarize up for me why big-notch companies such as J&J (and others I presume) took so much longer than Pfizer / Moderna?

Oxford was also pretty fast to develop their adenovirus vector vaccine but f'd up the trial. They already were doing extensive work on coronavirus vaccines which made the task much faster. The nature of the mRNA platform is just very very fast since all you need is the virus genome to be posted to the internet as a Chinese researcher did.

Isn't a vaccine just a weakened form of the virus?

At what point (when you already have a compromised immune system) does it not seem.... possible, that a vaccine could have more negatives for SOME VERY VERY FEW people?

No, I'm not suggesting anti-vax shit here - just asking a question.

Modern vaccines (subunit, mRNA, viral vector) work differently than older inactivated virus vaccines. A reasonably decent illustration of how an RNA vaccine works:

These mRNA vaccines are new and different. It's certainly possible that people have bad reactions to the vaccine (allergic or otherwise). I'm merely hopeful that the bad numbers could have an alternate explanation.

Anyway, I don't know if "weakened" is really the right word for a traditional vaccine, but I have heard that many times. If I understand correctly, I think it's supposed to be unable to reproduce in your body.

We've got about 14M doses in and just a really limited amount of anaphylaxis. I'm skeptical that the vaccine actually caused those deaths until proved otherwise. I'd want to see a clear trend that there is a death rate above the expected for that group who has been vaccinated compared to peers. The news is running with a lot pointing out X person died after getting the vaccine but failing to mention the cause of death is VERY unlikely to be related.

 

[ch33zw1z]

Given the shambles that a lot of states/counties are in trying to do this it seems like a good move.

https://twitter.com/i/web/status/1350183143031119877

Yup, seems like a good idea. Gotta get the plan in gear pronto, way behind.

 

[Red Squirrel]

From my understanding the way coronavirus kills people is by basically your own immune system overreacting and causing lung liquid to build up and other reactions of that nature. So could it be the vaccine deaths were similar, that the immune system just overreacted to it? Maybe it's the thing of giving certain groups of people a smaller dose if they can narrow it down.

 

[CZroe]

From my understanding the way coronavirus kills people is by basically your own immune system overreacting and causing lung liquid to build up and other reactions of that nature. So could it be the vaccine deaths were similar, that the immune system just overreacted to it? Maybe it's the thing of giving certain groups of people a smaller dose if they can narrow it down.

I don't think it could happen that way since the spike protein doesn't carry RNA to replicate in new cells or trigger cell death.

 

[Murloc]

From my understanding the way coronavirus kills people is by basically your own immune system overreacting and causing lung liquid to build up and other reactions of that nature. So could it be the vaccine deaths were similar, that the immune system just overreacted to it? Maybe it's the thing of giving certain groups of people a smaller dose if they can narrow it down.

AFAIK the vaccine can cause a short reaction due to the immune system reacting, but it's not the same thing as a full-on infection.
The lung issues with the real infection usually appear only after 5 days when the infection moves down there (and not everybody have that happen, but the ones that land in hospital did).

The point stands that if you vaccinate people who are about to die, some of them will die shortly afterwards in part due to pure chance, and in part because getting a fever for one day was the last one-fingered push over the brink they needed to croak.

 

[Red Squirrel]

Makes sense, so since it's not an actual infection then there's no reason for immune system response to last long. And yeah if they were already about to die then the vaccine probably did not play much of a role in that.

 

[Ichinisan]

From my understanding the way coronavirus kills people is by basically your own immune system overreacting and causing lung liquid to build up and other reactions of that nature. So could it be the vaccine deaths were similar, that the immune system just overreacted to it? Maybe it's the thing of giving certain groups of people a smaller dose if they can narrow it down.

Perhaps these elderly / vulnerable / at-risk people are already more death-prone than the average person, regardless of whether-or-not they received a vaccine. These deaths might be unrelated.