Not sure what we will run out of first, new variants or vaccine deniers?
Yup. They all deserve a Darwin award. Of course we're all going to need to chip in if we do it posthumously.
The thing is, as has been mentioned, vaccine and/or new vaccine production is going to have to ramp up to astronomical proportions if we're going to beat out the next variant and I don't see that happening.
How much fuckery can it do to the fuking spike at still be a functional key??? this is bs. Cheating.
Excellent question. If there are 380 bases . . . I forget how many bases there are per protein codon. Google says 3 per codon so that about 130 codons. That still leaves a lot of room for variants. I just guessing here but if that's the case, what probably matters most is the tip.
But even if that's the case, there should still be a number of tip variations that can trigger a cell to engulf the virus. The only difference will be how strongly they link to the docking site. Stronger docking should result in greater virulence if the rest of the virus remains as good at causing a cell to replicate it as delta is.
Not a virologist here so my guess is that if you have 32 variations in just the spike protein, the odds for this virus being as virulent might, just might not be quite as good. But we'll have to see.