I've known people to use tranny fluid in their engine's to free sticky hyd. lifters, so it's not that bad. You just don't want to drive it TOO much before you change the oil again. Also alot depends on the ratio of oil to tranny fluid. Tranny fluid IS a lot thinner and if he has too much fluid in there it will cause several things to happen.
#1 The cylinder wall's may become scored.
#2 The engine bearings may be damaged.
#3 The valve seal's may get worn.
But once again, if he has say 70/30 oil to tranny fluid (or more oil less tranny fluid) he should be OK for awhile, as long as he doesn't drive it too hard or let it over heat.
EDIT: Also a LOT depends on the age and overall condition of the engine. If it's a older high milage engine your apt to do damage quicker. But if it's a new car and still under warrenty, change it right away, as it may void the warrenty!