Thunder-Strike, as a refresher, is a Dual Processor system with quad 1080's, running WinTen. I'll have to review the documentation to be certain, but I believe the way I have the GPUs installed, three of them communicate (are PCIe linked) with the primary CPU, and the the last one communicates/links with the secondary CPU. I think the primary CPU is getting over-provisioned, thus not having enough spare threads to properly feed the GPUs linked to it. I was wondering if anyone could tell how to set the BOINC Manager to use only one CPU (affinity?). Then I can have a 2nd BOINC Manager configured to use only the secondary processor. That way I can ensure each CPU is reserving sufficient threads to run GPU projects at maximum efficiency/productivity. I almost posted, then had a thought....I guess I will need to also know how to tell the BM to use certain GPU slots as well.