For VR with proper eye tracking and foveated rendering, i agree. With the ability to setup the size of the foveated rendering field to adjust to individual users eyes and preferences, no one would notice the difference. But while thinking about it, only using a blurring shader or such a technique would not be the best solution. Really decreasing the resolution outside the foveated rendering field, would give more performance benefits. Then adding a blur effect to minimize jagged edges and less anti aliasing is needed as a bonus. Yes, that would work fine.
By foveated rendering I'm referring to the gradually decreasing resolution used outside of the central focus area. On top of this you then often use a blurring shader, to mask the transitions in resolution
A DoF filter would be a replacement for the normal blurring shader, since it is essentially a blurring shader that takes depth into account. Also the DoF filter would also be applied within the full resolution center region, since this region is generally big enough that you could have objects of widely differing depth position present (even though the user would only be focusing on one or the other of these objects).
Maybe those primitive shaders would help a lot in such a render example.
I imagine something like AMD's ID buffer might be useful here.
It would be as if it has reversed tessellation for outside the foveated rendering field.
With foveated rendering the traditional approach is of course to simple reduce the resolution the further away you get from the center of the focus area, but I don't see any reason why you couldn't also reduce any number of other features such as for instance geometry detail (i.e. reverse tessellation), or jerry rigging the normal LOD systems already present in game engines to work not just based on Z distance, but also on X/Y distance to the focus area.
One problem with this though is that it would probably require a fairly significant rewrite of game engines, but hey VR in general tends to require this already to get the best possible results.