My wife of a Professor of Biology with advanced degrees including a doctorate in molecular genetics. We agree it's merely a matter of time before designer organisms create ecological havoc by accident or design. A high school kid with the right kit can do more than the entire scientific community could a few decades ago. Fast forward 50 years, but on the bright side we're checking more "tipping point" boxes on climate.
As I look around it isn't a question of if we will destroy ourselves but if it can be prevented.
Pleasant dreams
Perhaps this is the solution to the Fermi Paradox, that any technology will outstrip the wisdom of its creators.