Haven't had any issues with either game (using a controller in both, of course... Keyboard has always been iffy at best in sports games).
At the same time, a lot of people prefer consoles for games that do well with a controller and expect a PC title to have decent mouse and keyboard implementation unless specifically advertised otherwise.
Anybody out there thinking about picking this up should be aware that 2k Sports has been putting very little effort into their PC ports lately.
Interesting. I was under the complete impression that 2K* sports games are much better than their EA counterparts from most sports nerds I know on the internet. Is that true or is it just that those people hate anything EA in general?
I can't speak for your friends, but I've bought and enjoyed previous 2k sports on a console although I don't think the MLB2k franchise is anywhere near The Show franchise for baseball. However, I made the mistake of picking up a few of the 2k sports titles for the PC due to a great steam sale and they were complete disasters.
It appears that my fears are well-founded regarding this 2k port, as Gamespot just rated it a 5.5 (
http://www.gamespot.com/pc/sports/majorleaguebaseball2k10/review.html) with the following criticism: "wide-ranging glitches ... make the PC port a much more troublesome game than its Xbox 360 and PlayStation 3 cousins."