Generally speaking the differences between namebrand RAM and unbranded RAM isn't always quality, but it's reliability you're paying for. When you buy RAM from Micron or Crucial, you know you're getting RAM from a quality cleanroom. Otherwise, it could have been made in someone's basement in West Virginia. Which RAM chip would YOU trust? 😉
ValueRAM is pretty good. I run a 256 chip in one of my systems and it hasn't failed yet. I would have to say though...if you're ever running it in a server, the server should require registered ECC RAM anyway, but that's the best to have.