I have this program, where that if it loads a midi file, it can seperate all the channels, and you are able to edit each and every instrument or a channel at a time....and kind of mess around with the midi file.
You could use a program like audacity to open the mp3, and edit the channels. Catch is there is usually only mono / stereo channels (not individual channels for each instrument). If you're looking to edit the mp3 file on an instrument-by-instrument basis, I think you're out of luck.
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