I have heard everything from yes, to no. The one I have heard the most is that if you are planning on using the laptop plugged in for a really long time (more than a day), then you should let the battery run down to about 60% and then pull it and store it in a cool, dry place.
I never did with my MacBook, but the only time it was plugged in and not moving for a while was at home, when I had it at school i was constantly moving it around the room for projects and whatnot.