Just setup my K8N Neo last Friday. This is my first MSI product and has been been rock solid (Running FarCry for hours...), one week by now, without any hang, blue screen, or setup problems. I run it on stock for 3 days, then slightly overclock my A64 3200+ (Newcastle) to 11x219 = 2.4 GHZ (11x200 = 2.2GHZ default). Sure depending on the CPU core you could have the temperature misreading problem, which is the only problem I have.
I haven't try any other FSB setting, just jumped strait ahead from 200 to 219 since I was aiming for a 200MHZ increase. But since I have the temperature misreading problem I'm afraid to overclock more, this should be solved in a future BIOS revision. Also I read (Don't remember where) that overclocking to a high HT frequency could corrupt the RAID array; and I'm not in the mod of reinstalling my PC. I'm just waiting for an official BIOS revision that address the temperature problem, making a good image backup of my drive, and then then maybe I would try overclock more.
So, if you follow some setup guidelines, and chose the right components, this MOBO should work pretty well. My best advise: Browse the forums and learn the problems and solutions before setup. You can start by the following thread at MSI forums (
http://msihq.designlab.info/thread.php?threadid=51994)