I love comics, but don't read a lot of mainstream superhero stuff because the characters are generally about as interesting and multi-dimensional as a slab of cardboard. Consequently the movies are, too.
The Iron Man movie trailer was so good, I ended up reading some of the comics. ("Armor Wars" and "Extremis".) Whoa! For once a mainstream superhero that has actual human characteristics and story potential. I'm definitely going to see the movie.
Frankly, I don't see how the game experience can be anything but crap. Iron Man slugs it out with baddies, sure, but that's what million other superheroes do. Even his "powers" (really his armor's abilities) are rather generic - flight, energy shields, energy rays. If you make an Iron Man game about just this, IMO it's like making a Ferrari game where the focus is on running an Italian car factory and maybe taking some test drives round the factory test track.
I think an Iron Man game staying relatively true to source material should really be about tactics. Tilting the odds in your favor by customizing the armor's abilities and manipulating the conditions. Managing/balancing the armor whilst fighting, using power when it counts. Lots of interaction with the environment - destructible and deformable structures, liquids, things under pressure, electricity, and so on. In a fight this guy runs on ice cold calculation, not intuition and feelings like some Spider-Man or Hulk.
That's one thing distinguishing him from the masses. The other is that he is vulnerable and human. Crazy rich and not ashamed of it. Trying to deal with the consequences of being an arms dealer, coping with alcoholism, etc.