You actually can but it takes time and money.
Get Acronis TrueImage with the Plus AddOn (about $66).
Install an Internal Drive (or external eSATA) on a computer and install the OS and the software.
Back up the installed Drive using TrueImage to another Drive (or to another computer through the Network). You must use the version according to the CPU, if you do have x64 you have to use x32.
Re-Ghost the backup to the Original Drive using the BackUp image and configuring TrueImage to use the Plus AddOn.
Send the drive to the Uncle, he can put it in a computer. Because the Drive was Ghosted with the Plus AddOn, it will adapt almost to any new Hardware.
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