These are always interesting topics. My practice is a somewhat unique one. I have 4 Seagate 120 GB drives, 2 SATA and 2 PATA. Here's how I use them. The two SATA drives are in a RAID 1 array - that provides a mirrored backup. That array is only for DATA - no programs or software.
I use one PATA drive as my main drive for OS and programs - and a second PATA drive as a total clone of the first. I the backup PATA, or reserve drive, is not connected power wise unless I wish to clone the active drive to it. I do that after major changes and upgrades or new programs.
After cloning, I then switch the drives by changing the power connection. This lets me rotate those drives - usually every ten days to two weeks.
This has worked for me for several years. My next system will have 4 SATA drives in two RAID 1 arrays, and that will give me a good redundancy base. One for data and the other for OS and programs.
I have used Hitachi drives quite a bit, and never had a problem with them. But now, I prefer Seagates.