Gotsmack,
If you did not purchase the MB yet and really want to make sure it supports Prescott, then you may want to wait to ensure that they are compatable, which may be a month. Or get the Intel 875P Chipset Motherboard for Intel Pentium 4 Extreme Edition CPU, Model "D875PBZLK FMB 1.5" now which will likely support it. Funny thing is that Intel did not spec this MB to the FMB 2.0 spec which Asus and Gigabyte are shooting for.