the SPECIAL is irrelevant; they balanced the game so that *any* build works just as well as the next. if you want OP guns, go with 10 LCK, otherwise a average build will do just as well.
or 9+ bobblehead.
btw, INT no longer gives you skillpoints. there are no skill points at all.
every level, you get ONE pick out of 1) any stat +1, or 2) a new perk. (you can stack more than 1 of the same perk)
perks now replace stuff like Lockpicking and Sneak - the more perks, the equivalent of higher skill % in F3. (i.e, 4 perks in locks is 100 lock)
the game is not about minmaxing. just pick what you like and roll with it, it will never punish you because of it.