I just got mine Friday. I haven't actually USED my system in it yet, since I'm waiting for a hard drive, but...
It LOOKS really nice. The "semi-styled" look you'd expect from Dell or something. Not over styled like store bought stuff, but not completly plain.
It IS big, but not too big, as someone said. I'd say it's maybe 25 or 33% bigger than a "normal" mid-tower case from Dell, maybe half a foot taller.
The two fans it comes with are pretty quiet. You can definatly hear them, but it's pretty normal volume level. Maybe half as loud as the case I'm replacing (and again, I think pretty comprable to a Dell case). I think it'll be a manageable volume level.
The case is REALLY accessable. The only better designed case I have is Apple's G4 case that folds down to the side.
My i815 motherboard looks positivly small in there, so sliding in the motherboard, hooking up the drives, etc., is very easy. The only "issue" with this is that the top 5 1/4" drive bay (there are 3 5 1/4" bays) is really a bit too far for a regular IDE cable. So if you're using IDE drives, plan to install them in the bottem two slots.
Drives install very easily. You screw mounting side guiderail things to the sides of your 5 1/4" drives, and then just slide them into place. They click in place, and can be easily removed. The floppy drive bay is screwed in place with thumb screws, and you screw the drive into the drive bay.
So in other words, all the drives are screwed in outside of the case, and then you just click or slide them into place.
The hard drive bay has a latch to quickly attach and remove it. Someone mentioned it's hard to get it to lock. I've found when I first slide it back in and try to close the latch, it dosn't go all the way. Just push slightly harder and it'll go in the rest of the way and the latch closes easily.
There are four places to click fans into place (I think for 80mm fans). It comes with the back two slots filled, and the front two empty (not sure that I'm going to bother filling them, since I don't think my system would generate a super high amount of heat). There's also a slot in front of the hard drive bay, but I think it uses smaller fans (not sure what size). But that's probably great if you're using SCSI drives.
The side of the case opens easily (it's screwed shut when you first get it, but then you can just use a built in handle). With the side of the case off, the front of the case over the drives comes off easily.
The only other "issue" I had with it was just that it took a few tries to figure out exactly which holes to screw the drives into. When I first attached the floppy, it was too far back, second time too far forward, and I got it right on the third try. It's really easy to change though, since you have the drives in your hand while you're screwing, and then just slide their them into the case.
I somehow got the case to "draw blood" too, but I have no idea where or how, and I've even had that happen on my G4. All the edges are rounded, and it's very open inside, so this is a very "safe" case to work in.
I'd highly recommend this for anyone, whether you've built a lot of systems, or this is your first.