1. Disable System Restore
2. Reboot into safemode
3. Fix the following using HJT:
O4 - HKLM\..\Run: [WildTangent CDA] RUNDLL32.exe "C:\Program Files\WildTangent\Apps\CDA\cdaEngine0400.dll",cdaEngineMain
O4 - HKLM\..\Run: [TkBellExe] "C:\Program Files\Common Files\Real\Update_OB\realsched.exe" -osboot
O4 - HKCU\..\Run: [Weather] C:\Program Files\AWS\WeatherBug\Weather.exe 1
O4 - HKCU\..\Run: [Smile Brush] "C:\Program Files\Smile Brush\Smile Brush.exe" a
O15 - Trusted Zone: *.musicmatch.com
O15 - Trusted Zone: *.musicmatch.com (HKLM)
O23 - Service: License Management Service ESD - element5 - C:\Program Files\Common Files\element5 Shared\Service\Licence Manager ESD.exe
Remove, The Weather Bug, Wild Tangent, Smile Brush via add/remove programs
then run adawareSE and spybot with updated definitions on both