I haven't done any controlled experiments.
For a while I was planning to buy this chipset cooler. It IS a nice cooler for a chipset.
I also see that ASUS has already placed a fan on the A8N-E's Northbridge chipset.
Here's my experience, which deterred me from buying an HSF for my chipset on an ASUS P4P800.
I went through two heatpipe coolers on my "MOJO," giving up the ThermalTake PIPE101 easily for an XP-120. By that time, I decided to duct the motherboard, CPU/HSF/VGA and memory for quick and efficient exhaust out the rear of the case, so that the front intake fans fed the CPU fan working in series with the exhaust fans.
Before I ducted the motherboard, I had suspended a 40mm Sunon Mag-Lev fan above the chipset cooler with a Zalman fan bracket and a replacement screw-mount for the Zalman assembly so that I could hang the Sunon very close to the chipset heatsink.
Keep in mind that all these things contribute to temperatures taken off anything else: CPU, VGA, chipset, memory -- all connected by circuit traces which also conduct heat. Cool down one -- their hearts and minds will follow.
My chipset temperature at that time was just a few degrees F either way around my VGA idle temperature, which has an extremely effective Zalman ZM80D heatpipe cooler and OP-1 option fan. The AGP card usually idles somewhere around 32C to 38C depending on room temperature. The load value is something considerably lower than 110F or 45C.
After ducting my motherboard, the chipset at idle is some 8F lower than the AGP at idle and only 2F higher than the CPU at idle (Northwood 3.0C@3.6Ghz with either stock voltages or voltages well within manufacturer's "Maximum" approved.)
The chipset never seems to go over just in excess of 40C even when running PRIME95 Torture-Test LargeFFT. I could test that again to verify, but that's what I recall.
Again, the Swiftech is a really nice chipset cooler. It costs about $30-something, which is a night out for one person at a decent restaurant. But a Sunon 40x25mm mag-lev is something like $6, a Zalman bracket was once on sale for less than $9, foam-art-board is about $6 for 3'x2' (of which you only need about a third to make a ducting mod), Lexan for a ducting mod probably costs about $10 or $11.
Anyway, your ASUS board already has a little fan on the chipset. Have you stuck a thermal sensor on that chipset or as close as possible underneath the base of the HSF to see how hot it gets?