Well if you want the best experience in games, you will want to make sure 4 speaker mode or dd5.1 is selected when you play your games, that way, the game will output to 4 speaker mode when the information is there. I don't think having dd5.1 selected when playing a game is that important because most games don't use dd5.1. But I would make sure it is selected anyway. As far as speaker placement goes, make sure you try and have two front speakers on the right and left of you, one directly in the center (on top of the monitor works good), two behind you, and of course the sub on the floor. I think that should be pretty well optimized for games, dvds, music, whatever