If you're really bent on minimizing it's usage you might want to set it to a fixed, small size, but don't disable it.
I seem to remember having a heck of a time on a few systems that I worked on when I had to go into safe mode on Win2K and there was no swap file ... it would given an error about not having a swap file then log me right out ... I couldn't get in to work on Windows or set a new swap file. It was a hellish mess. In this case though the swap file was missing because hard drive partitions changed ...