As others have pointed out, the airline industry is having a tough time and is not likely to get better any time soon. There is good news and bad news about getting a job with the majors. The good news is that many of the current senior pilots will be looking to retire in the next few years. They came from the Vietnam military ranks mostly. The bad news is that many of the pilots currently in the military will take those jobs.
In general, commuter airlines (not majors) are looking for a minimum 1,500 - 2,000 hours flight time with the majority being twin-engine and/or turbo-prop time. Majors now require 2,000 - 4,000 hours of PIC time in turbo-prop or jet.
Some will suggest getting your time as an instructor. This is ok to a point. Commuter airlines will not even consider any hours in a single prop airplane. So, you need to get multi-engine time and any turbo-prop time you can get. This means running mail, packages, medical, whatever that can be done in a multi-engine or even better a turbo-prop plane.
And a final word of discouragment....
Flying for the average commuter pays about $10.00 an hour. They tell you when and where to fly and that means you move to where they need you. Commuter airlines make money flying from podunk towns to hubs so you can expect to live in less than exciting places. If your ok with that and all else I have stated, then best of luck...
from one who's been there done that and don't any more....