Starbuck,
Don't feel too bad about the time you spend picking these things out.
I'm in the same predicament and just joined up to find some help in making my decision - which will be in about a day or two now after keeping a running and constantly changing wish-list over at newegg for about a year now.
Most of that time was just waiting on availability of funds what with getting a house, a car, putting a kid through school, going through two hurricanes... you know, life. On top of that, I've also got some massive software upgrades to do too given my profession.
I'm in architecture and work almost exclusively with AutoCAD and render with Accurender. But besides that, as a hobby, I record my vinyl LP's and make my own cds of them. I'll spend hours and days cleaning every click and pop I can hear.
With that, I can't get a true dual processor MB (too much for that and the 2 cpu's) so I've settled on the Nforce Ultra and an X2 AMD. SLI is useless in Acad and Accurender (AR) which is pretty much strictly processor driven. AMDs also tend to run Acad and AR much more efficiently than Intel. AR is also multi-threaded so the X2 will be a big advantage there - on true dual processor machines, renderings really are done in nearly half the time (I once had a dual Athon MP 1800+ at work). I'll do renderings that take days to render and top out the cpu (both of them whether logical or physical) at 100% the whole time, so I'll need something fairly stable.
With all the motherboards tossed about in this thread, no one's mentioned (unless I missed it) the AOpen nCK804Ua-LFS. There are almost no reviews of this board and maybe that's the reason no one'e mentioned it, although the few posted reviews at newegg seemed to like it.
One thing going for it for me is the 2 com ports - yes, that's right... the 2 serial com ports.
Why?
I have a 12x12 Calcomp digitizer tablet I use for Acad - it uses a serial port connection. I also still have an old m100 Palm Pilot that still used the serial port hot sync. No one makes the USB version for this pda that was once available for what seemed like 2 days.
If I got a MB with only 1 com port or no com ports, I'd have to add a PCI to Serial port adapter (either the one or two port kind, depending) for another 30 to 40 bucks.
I know that AOpen isn't the only NF4 MB with 2 com ports. So does the Chaintech VNF4/Ultra and the BFG Tech which as I understand it, both are really the same board anyway.
Just reading everything on all the other MBs, I too got a little scared at first with all the issues that are brought up. But then, as posted elsewhere, no one posts what a great board they've got - only the problems they are having. And, I suppose every board will have issues given the nearly infinite possibilities of configurations and parts.
I've had MSI, then Foxconn, and now Asus on my list. But I'm also considering the Abit KN8 Ultra and the DFI nF4 Ultra-Infinity (the only DFI I found that had an LPT port too, which I also still need), all at lower prices which help make up for having to add the com port card to maintain 2 serial ports total.
I'll be keeping an eye on this thread.