It could work, it could not work. Many jobs can be done adequately by someone who is a quick learner and applies himself even with no prior experience. I would think about what skills are required and how well I match up. Some employers will give off a vibe regarding at what level they expect the person to perform from day 1.
My last job was one in which I had zero experience and the offer was to be the manager of the group. I figured it this way... the group itself was experienced, there was no major upheaval in what was to be done, so I took it and did well. I worked like a dog learning the terminology and priniciples of the field, and focused on how to improve the process and results rather than learning every nut and bolt of how they did the work because the group already knew that part. When someone new started, I assigned another person to mentor them through the details. I never tried to fake it, though... that just makes you look like a phony.
On the other hand, I would not take a job as a mechanic because I know that's a job I could not do well at no matter how hard I worked at it. My skills are not a good match.
If you think you have the basic skills to succeed, and you feel the company's expectations are reasonable (in other words, you will have time to ramp up to speed), then go for it! What's the worst that can happen?
Remember, even if you are a complete failure, you can put that position on your resume and now you have experience in that field!
