some of my coworkers use it so they can access their outlook email and calendar and stuff
our exchange server is not the latest version so the web interface to thecalendar stuff doesn't show up right. in addition, it doesn't pop up appointments like outlook. also if you have your email categorized into subfolders, you can't tell there are new emails by looking at the subfolder you have to actually go into each one.
w/ crossover office (it's just wine customized to work w/ office, rite?) it works no problem. but having excel spreadsheets w/ multiple tabs doesn't really work well in crossover office and office 2000 installed on it.