Has anyone tried shooting at the
driver, not the vehicle? I've had four vehicle-vs-vehicle kills that I remember, plus several on-foot vs vehicle.
- Friend's back pay, Banshee (random encounter)
- 2 bikers in the tunnels
- not Ivan, first ULPC mission, sports car, through the rear window
I was particularly happy with the Banshee kill. I fired one shot wildly while trying to orient the reticule. The target hit a few cars waiting at a light, slowing him down. The second shot went in his head. Time to kill: under 20 seconds. Completely luck, not skill, but I'll take it.
It's been my experience that cars can soak up a lot of gunfire, especially from the rear. My impression is that they're more durable than in previous GTA games, but I haven't played them recently enough to say for sure. On the other hand, cars are not the magical shields they used to be. I'm sure everyone has taken damage while driving away, and not always from a gunman standing right next to the side window.
Of the chases I remember (aside from the final mission), only one strikes me as definitely no-kill: the one where they crash into the fountain. IIRC, there are specific instructions to take them alive to recover the package.
I won't claim that shooting the driver is efficient (I sprayed 300-400 SMG rounds at the 2 bikers) or the right tactic for mission completion, but my experience is that it's
possible.
Xavier434's drive-by technique has the advantage of a closer target.