depends what you're doing...
also, glass for windows or glass on eyeglasses? windows - i'd go with glazed or annealed, double-paned glass. better looking, insulates, toughened/tempered glass can be strong as hell.
eyeglasses? polycarb for sure. lighter, cheaper to replace, doesn't SHATTER into a zillion pieces that will turn your cornea into pulp, etcetc