So, after several weeks tweaking my systems for the upcoming race, here is some advice. 1) Unless you don't have GPU cards to fold with, CPU points for F@H are currently almost not worth turning them on. For example, so slowest video card I have in my "farm" gets 200,000 ppd average. The BIGGEST CPU machine has 24 threads, and it gets 40,000 ppd average, and uses way more electricity. 2) Todays cards require very strong CPU individual cores. I think the fahcore_21.exe is single-threaded. (don't hold me to that). SO.... turn off hyperthreading in boxes that support that, and again, for GPU boxes, I don't recommend that you even allow F@H to create and run the CPU (or SMP depending on your version). Also, if you have a choice, and multiple boxes, pick the strongest single-core box for your video cards to run in. 3) Using older technology boxes for your video cards (like PCI-e 1,0) or DDR2 ram , etc, can hurt your ppd. Almost any socket 775 motherboard is a bad idea. Better than nothing if you don't have anything newer, but will hurt your GPU ppd. 4) I am fairly confident that Windows 10 has a fair superior "scheduler" and may help your ppd over win 7. For me, I really saw a difference. Below is my current farm. The descriptions tell you what CPU and what video card that line is for. If you have questions, please let me know, we really need to get the best out of our hardware for the upcoming race.