Cersei sums it up best: "In the game of thrones...You eithier win the crown or you die"i should know better, but i think almost all of the characters still with us from season 1 are safe from the fat, bearded angel of death known as grrrrm:
tyrion - seriously, no tyrion = no GoT
sansa - that would be a HUGE shock, especially now
arya - nope
hound - maybe. like i said before, he better go out in the fight of the century and not drogo out on us.
jon snow - nope
raisin bran + hodor - bran is obviously a central element, but i fear for hodor
rickon rickoff and whatshername - ???
theon - theon already died, and reek is safe as ramsay's pet
baelish - remove him, and what's left? nothing we've seen so far fills his shoes
varys - that would be a real shame, especially since he's got his own power play on simmer
cersei - revenge murder is the only way for her to go out. take your pick as to who dishes it out.
jamie - maybe. he's pretty marginalized after a great story (and performance) upon returning to king's landing. has he peaked?
tywin - either age or revenge/war, feels like it's coming soon.
danerys - nope
friendzone - maybe the next time we see him?
who am i forgetting? shae and michael bolton first appeared in s2, but i can see either of them hankering for a shankering. ygritte will die in jon snow's arms, maybe by his hand - you heard it here first.
remember, the only rule in the game of thrones is smart people survive.