Originally posted by: VirtualLarry
Potentially - noise, heat, and space. Most modern tower PC cases, have little "fins" that seperate the 5.25 bays. You may have to bend those back, to install a "full height" 5.25 drive.
I'm kind of curious - why in the world would you want to install something as ancient as a full-height drive, these days?
You can get working 1" (or maybe just half-height) 4.5GB U2W SCSI HDs for under $10.
Also, something as big as a full-height drive, will probably have very low capacities, probably less than 1-2GB. (I have a couple of full-height 20MB MFM drives, if anyone wants one...)