MS' DVD/USB tool, HP's floppy and fake floppy flash drive tool (forget the name), Pen Drive Linux's utility, and unetbootin's utility, see and use them fine. They also show up as USB-HDDs in any mobo form the last, oh, I don't know, 8 years, maybe?
For potentially bootable media, you want the RMB to be false, so that it does show up as a local disk, ensuring that the partition table can be read, the MBR can be read, and that you can always mount it async, if you want, and that a mobo that checks it won't deny you the USB-HDD boot option. Only with 2K/XP, where it assumes that a local disk is a cold-swap-only internal drive, should there be any problems. Luckily, though, most of the time, that setting is ignored, since it was set based on Windows behavior of the time, rather than being a useful setting. The only fixed disk is a modern Windows install should be the C: drive, and any profile-containing drives, if you went and made links for a SDD/HDD hybrid setup.
As for the OP, Corsair and patriot both have some nice USB flash drives that are particularly fast, able to saturate USB 2.0, and make good use of USB 3.0. Nothing on a regular retail shelf (Fry's, TD, cemra shops, etc., may be different) will be fast.