Let me make some suggestions for fans.
The Fractal Design case comes with three of their 3-pin 140mm fans pre-installed. Now, 3-pin fans can have their speed controlled ONLY by a fan header that uses the older Voltage Control Mode (aka DC Mode). The newer 4-pin fans can be controlled that way, but better by using PWM Mode. Your ASUS mobo has several fan headers and each, as I understand them, can be configured to use either type of control method.
In general, I think it best to use a mobo's automatic fan control systems to cool your equipment. There are normally two of these. One controls fans plugged into the CPU_FAN header and the CPU_OPT header, and this is based on the actual temperature inside the CPU chip and measured by a sensor in the chip. Hence it is ideal for cooling your CPU. Moreover, the actual CPU cooling fan NEEDS to be plugged into the CPU_FAN fan header because of special monitoring of that fan by the mobo for possible fan failure. The other system normally controls fans on the CHA_FAN1 and 2 and the H_AMP_FAN headers, and it uses a different temperature sensor built into the mobo; this is ideal for case fan ventilation control.
The Case comes with a Fan Hub included. It is capable of powering many fans without being subject to the mobos' fan header power limits because it gets fan power directly from the PSU. But it NEEDS a PWM signal from a mobo fan header and it will use that to control ALL of its fans in the same way. This particular Hub appears to have a special feature: it can power and control both 3-pin and 4-pin fans, and it has output ports for both types. It does this by "converting" from PWM Mode to Voltage Control Mode.
I suggest you connect your CPU chip cooler to the mobo CPU_FAN header and let it do its normal automatic control function. For all the case ventilation fans (the three in the case, plus any others you might add) plug them into the case's Hub. The Hub has a cable from it ending in a 4-pin female fan connector that must plug into a mobo fan header. It has two functions: pick up the PWM signal it needs for control, and return to the mobo the speed signal of only ONE of its fans (the one on Port #1). Now, the manual says to plug the small cable into the CPU_FAN header and then plug your CPU cooling fan into Hub Port #1. This is ONLY to ensure that the Hub actually gets a PWM signal, and it has the DISadvantage that it puts all fans under control of the CPU's internal temperature sensor. I recommend a different scheme. Plug only the CPU cooler into the mobo CPU_FAN header. Plug the Hub's cable into the mobo CHA_FAN1 (or 2) header, and ensure in BIOS Setup (manual, p. 3-7) that this header is configured to use PWM Mode so that the Hub will get that important signal. Now connect your case fans to the Hub ports. I advise ensuring that one of those fans (even a 3-pin fan if necessary) be plugged into the Hub's 4-pin Port #1 (see case manual p. 7) that is labeled for use with the CPU fan. This will ensure that the Hub has a fan speed signal on this port that it can relay back to the mobo CHA_FANn header so that the mobo does not believe that the chassis fans all have failed.
Be aware of a factor in using the Hub or any such device. Any mobo fan header can accept the speed signal from only ONE fan. So, any Hub (or Splitter) that connects several fans to a single header will relay back to that header the speed signal from only ONE of its fans. The mobo header can monitor that signal for fan failure, but it can NOT monitor any other fan on the Hub for failure. So it is up to you to check from time to time that all your fans still work.