I would think that most closed-bottom heatsinks would benefit from a crossflow setup, but you'd have to rig up some kind of duct and heatsink housing to be sure the air actually went across the fins. Other than that, just experiment and see what works better as already suggested above. But I suppose that the convention is blowing into the fins for a reason - probably the fact that air, like water and students takes the path of least resistance... So unless the fan is tightly coupled and sealed to the heatsink, most of the air drawn by the fan would not be passing thru the fins to any degree if it could be avoided.
.bh.