Replacing my MSI 650i with an eVGA 750FTW tomorrow, in fact !! I would have gone with the MSI P7N had MSI not screwed up the CPU support tables, indicating that the newer chips worked in the P6N, which they did NOT. So all in all, the upgrade is nothing more than better CPU support on my end.
Actually, I was going for the 9450/9550, but settled on the Q6700, which would have worked just fine in my P6N. I don't consider it wasted money on the board, as my plan is to step up to a 45nm quad in December and then move the Q6700 into the MSI board. Its performed very well, but the crappy MSI support confusion has me ditching any future MSI board purchases.