Everything you wanted to know about glucose fructose syrup, sugars and starch.

May 11, 2008
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I am a person who reads the ingredients on my food because i like to know what i am consuming.
I thought it would be a good idea to clear a few things up for myself for once and for all and for others that may be interested. Also , adding a bit of proper information helps people who just loudmouth away without thinking.

High fructose corn syrup and the more general name : glucose fructose syrup.

High fructose corn syrup AKA hfcs, is as the c in the name implies made from corn starch.
In reality, glucose fructose syrup can be made from any starch or from sugarbeet or sugarcane.
glucose fructose syrup is the general name in the EU because in the EU mainly wheat starch is used if i am not mistaken.
Not much hfcs here but i would not be surprised that it is available in the EU.

saccharides are carbohydrates.
glucose (AKA dextrose) and fructose are called monosaccharides.
glucose (and starch) are a product of photosynthesis.
I am not 100% sure on this, fructose is not a direct result but it is synthesized by the same cells(chloroplasts) that do photosynthesis.
If anybody has detailed information, i am interested.
sucrose is called a disaccharide because it is made up of two monosaccharides called glucose and fructose.
Why do plants mainly have saccharides like for example sucrose in fruits.
Well, as it turns out monosacchrides like glucose and fructose are easy targets for bacteria and fungi to feed on.
And i have not yet verified this, but that is i assume, the main reason why plants store the saccharides as disaccarides like sucrose.
The glucose and the fructose are covalently bound to each other in sucrose.
Because it is more chemically stable then.
If anybody has detailed information, i am interested.
Most plants store glucose itself as starch possibly for the same reason and as efficient energy storage.
Starch is build up of 2 polysaccharides and the polysaccharide amylose or amylopectine is comprised of many monosaccharides glucose.
So all that is needed is to get the starch out of the plant and turn starch back into glucose.
Plants such as for example corn and wheat.
Fructose is generally separate or eather covalently bound to glucose to form sucrose.

Sucrose (AKA table sugar) is a result of a covalent bond between glucose and fructose.
This bond can be split by the enzyme invertase but many bacteria, plants, fungi, insects and some animals have this enzyme.

In humans and other mammals also an sucrase enzyme is used.
Enzymes that can do hydrolysis of sucrose are all called sucrase. Invertase being one of them.
This enzyme is called sucrase (isomaltase is also such an enzyme) in humans and produced by the duodenum(First section of the small intestine).
This is (what i have come to understand of it) because our cells can only absorb monosaccharides (because of the size , i think).
If anybody has detailed information, i am interested.
Monosaccharides are used for energy which is a long complicated process to ATP or either tryglicerides as energy storage.
Consumption of high amounts of fructose can lead to increase of tryglicerides production.
This is sure to be individual dependent, meaning for each person a different response but higly likely similar when looking between family members.
What happens to these tryglicerides and the overproduction of tryglicerides, i still have to look into.

Inverted sugar that is for sale is a disaccharide called sucrose split up into the individual monosaccharides glucose and fructose again by making use of acid (even lemon juice with sugar works) to split up the covalent bond or using the enzyme invertase.
As a sidenote, inverted sugar spoils much faster than sucrose (table sugar). See above why.

Most plants store in the fruits glucose but also have separate storage of fructose and glucose because these are not covalently bound yet.
It is an ongoing process of course.
So my question about glucose and fructose being separate and may being an issue is answered. It is not an issue.
The way carbohydrates are processed and split up in the human duodenum in colaboration with the pancreas and the Brunner's glands are for another post.
Because it is very complex and requirs a lot of glands and parts of organs to regulate ph value in the small intestines, to produce hormones and to produce enzymes.
As a sidenote, enzymes to function properly need the right ph value, the temperature is of course kept constant by our bodies.
To understand all of this, the body needs to split up in different smaller subjects that work independently but do rely on each other.
But that is for another post.

glucose syrup.
Glucose syrup can be made form any plant starch. Potatoes, cassave, rice, wheat, barley or corn.
With starch, the enzyme alpha-amylase is used to convert the starch to shorter glucose monosaccharides.
Chemicals can also be used, but for as far as i know, the enzyme is cheaper and inherently safer.
The enzyme alpha-amylase is also present in humans and other mammals.

glucose fructose syrup.
The glucose is converted to fructose by making use of an enzyme glucose isomerase.
The resulting fructose is then mixed together with glucose and water again to form the syrup.
How the enzymes are denatured, is for as far as i know is changing the ph value of the mixture and filtering it.
But i have no information on this yet.
If anybody has detailed information, i am interested.

Different levels of fructose in glucose fructose syrup:
hcfs 42
hcfs 55
hcfs 90
the number gives the percentage of fructose to glucose amount.
90 means 90% fructose, 10% glucose per unit of weight.
hcfs 90 is mixed with hcfs 42 to get hcfs 55.

I assume this is similar with the production of glucose fructose syrup from wheat or potato starch.
hcfs 55 is mainly used for soft drinks it seems, the others for food.
hcfs 90 is for as far as i know not used for food.
If anybody has detailed information, i am interested.

This leaves the problem to two possible issues :
Production of starch and over consumption of glucose and fructose.


Production of starch:
With corn starch , mercury chloride seems to be used by some sources.
But also caustic soda and hydrochloric acid is used to process the corn to turn it into starch.
To produce caustic soda or hydrochloric acid, mercury is used and when the process is not controlled properly, the caustic soda and hydrochloric acid can be contaminated with mercury which can end up in the hfcs.
Which is where all the news of mercury pollution came from in the past.
Should be resolved by now in 2017. (see second post about caustic soda)
On the wiki page there is mention of using mercury chloride directly on the corn seeds, but i have not found any detailed information how that corn to starch production process actually works.
If anybody has detailed information, i am interested.
Corn starch is mostly used in the USA because of the government subsidization for corn production and lobbying of the corn industry with the government.

Wheat starch
is more commonly used in the EU.
Turning wheat or potatoes into starch and into glucose.
Well, it is just cleaning, milling, washing and drying. This will become starch milk.
Then use the enzyme alpha-amylase.

Overconsumption:
Assuming that processed foods are laced too much with glucose fructose syrup:
Every person eating a healthy amount of fruits and vegetables should be aware that consuming processed foods aside will increase the daily glucose and fructose consumption.
Besides the calorie increase which will lead to obesity, there is still the problem of consuming too much glucose and fructose in general which can lead to cardiovascular diseases and diabetes and other metabolic problems.
Now as some here on the forum mention to reduce or stop consuming fruits and vegetables, which is just plain stupid because fruits and vegetables contain much more than just carbohydrates(saccharides).
It is better to reduce the amount of processed foods as much as possible.
A little bit of processed foods is nothing to worry about.
Eating a bit of pie is not an issue, too much pie every day is.
If you eat healthy all the time then consuming fried foods with a little bit ketchup or mayo, it is not an issue.
Avoid foods where sugar is added as well glucose fructose syrup and fructose on top.


The thing that is worrisome to many people including myself is saturating ones body with high levels of glucose or fructose or both.
Some researchers say it is a problem, others say it is not. The truth is that it is an issue but does not have to be when thinking about what you consume on a daily basis.
I have to look into that more by reading what actually happens inside the human body when consuming a surplus of glucose or fructose or both.
The (human) digestive system is really a biological marvel in that respect.
From literature it is known that when not al fructose is digested in the small intestines, the fructose will end up in the large intestines where the bacteria can wreak havoc by
converting fructose into molecules that can cause problems like excessive gas buildup or diarrhea. Not every person has this as it depends from person to person and the individual bacterial composition inside the large intestines.

Also, giving infants food with high amount of fructose will give digestive problems because the infant is not yet able to handle fructose.
However, fructose is delivered to infants with the mothermilk in very very low doses when the mother consumes her healthy amount of fruits and vegetables without any side effects to the infant.
Not an issue here either as long as there is healthy but moderate consumption by the mother.
Infant formula with high amounts of fructose can cause digestive problems and distress for the child which in turn will lead to crying and behaving difficult because the poor thing has a lot of cramps and discomfort.

Of course, some people have a genetic fluke that prevents them from processing fructose properly and this is called fructose intolerance.


Websites that claim hcfs is dangerous
Well, here one should have caution and a critical eye while reading.
I read a few of those websites and some are really bluntly lying.
For example the mention that glucose and fructose do not exist together in nature is laughable if one reads how plants store energy for difficult times.
The mentioning that fructose is 173 times more sweeter than sucrose and therefore more dangerous is laughable.
The websites that mention possible mercury contamination got something right. But that should no longer be the case.
Websites that claim that alpha-amylase is dangerous, ignore them. The human body produces this enzyme as well.


tl,dr:

Conclusion:
* highly likely hfcs should no longer contain traces of mercury in 2017.
* glucose fructose syrup made from wheat or potatoes never contained mercury, so no danger here.
* should you avoid all glucose fructose syrup with 42% fructose ? No, there is nothing wrong with it in moderate quantities.
* Should you avoid sodas with glucose fructose syrup 55% ? Yes, because of the high calories and tooth decay issues and because in a healthy diet you already will consume enough sugars. Sugar free soda or water is best.
* high amounts of fructose can cause digestive problems.
* high amounts of fructose or either glucose or both can cause cardiovascular diseases, diabetes and other metabolic diseases.
* fresh fruits and vegetables are healthy and better for you than processed foods. (And do not come up with that nonsense that fruits and vegetables contain more pesticides, where do you think for example the starch comes from in processed foods , you schmuck.)
* If you want to prevent getting obese and sick, try to keep a healthy caloric intake by consuming fresh fruits, (unsalted,unsugared,uncooked) nuts, fresh vegetables, moderate amount of meat, some moderate use of dairy products and avoid processed foods with added sugars as much as possible.
But for enjoyment, have some processed foods once in a while.
* Nuts and muesli are a very good substitute for cookies. Especially with some yogurt with fresh fruits.
* But do not forget that processed foods contain starch, glucose, fructose, lactose and more of those (pun intended). So the hidden calories add up quickly.
* Also, try to have enough exercise.


Sources:
I should have added all my sources but some are in different languages.
Sorry, i want to stay healthy all my life, so in all honesty i wrote this without the desire to creating hysteria.

edit: Removed some grammar errors.


Updated text by removing errors.
 
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May 11, 2008
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Well, good news for the production of caustic soda for corn processing and the possible mercury issue(At least in the EU that is) and for the environment.

Caustic soda is the byproduct of chlorine production.
http://www.eurochlor.org/the-chlorine-universe/what-is-caustic-soda-used-for.aspx
http://www.eurochlor.org/the-chlorine-universe/faqs-about-chlorine-and-caustic-soda.aspx#how-made
"
How is chlorine made?
Essentially, chlorine is made by passing an electric current through salt water (brine). There are three main production routes: the membrane, the mercury and the diaphragm process. Although most chlorine in Europe is now already manufactured using the membrane process, the industry is committed to converting mercury production units to the more environmentally-sound membrane process by 2020.
"
http://www.eurochlor.org/the-chlorine-universe/how-is-chlorine-produced.aspx
The three main technologies of producing chlorine are


So the big question is are caustic soda suppliers in the USA also using the membrame technology and are they phasing out the mercury technology as well. Or has it already happened and is hfcs perfectly save ?

For background information:
https://ehjournal.biomedcentral.com/articles/10.1186/1476-069X-8-2
http://www.icis.com/blogs/green-chemicals/2010/12/dwinding-mercury-cell-chlor-al/

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As it turns out some chlorine manufacturers in the USA did use membrame technology and some use the mercury technology at the time. But how is the present situation ?

Occidental Chemicals = mercury free.
http://www.oxy.com/aboutOccidental/Where-We-Operate/Pages/Chemicals.aspx
Olin = mercury free.
https://olinchloralkali.com/products/sodium-hydroxide/
ASHTA, on the website is no mention of selling sodium hydroxide (caustic soda).

PPG = unknown.
Pioneer chemicals = unknown.
 
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ImpulsE69

Lifer
Jan 8, 2010
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It is all solved by one thing. There is no need for all of what you posted. The body doesn't like too much of 1 thing all the time. It really doesn't matter what it is.

Everything in moderation.
 
May 11, 2008
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It is all solved by one thing. There is no need for all of what you posted. The body doesn't like too much of 1 thing all the time. It really doesn't matter what it is.

Everything in moderation.

Yeah, i edited my second post.
Seems hfcs should be free of mercury when the caustic soda comes from the plants that are mercury free.

I do not know if my list is complete, to be honest.
 
Mar 11, 2004
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Yeah OP, and after the "HFCS is the debil!!!" bullshit, they've been trying to hide sugars under all manner of different names on the label. Which, to be fair, is ok if they're just being open about what is in their stuff and they do still have to list the amount of sugars fairly simply after all.

High amounts of sugars (in any and all forms) and refined carbs is definitely a major issue with modern diets.

Oh and sugar free soda isn't best. Research seems to indicate it has just as many issues for overall health as sugary soda, and especially might be awful on our gut bacteria.

I'd also say you should moderate meat intake just as much as dairy. (And before the Atkins/Paleo dickheads chime in, if you're operating on a strict diet, then you could be fine if you adhere to it.)

You can't make blanket statements either. There's a lot of awful "fruit" products out there (dried fruits for instance, chocolate covered ____, etc), especially anything with juice in it. And some yogurt has tons of sugar in it (have seen a couple that have 20-30g worth, which is like 1/2 a can of pop's worth in a little yogurt cup).

So yeah look at the ingredients. And try to eat more fresh foods and less heavily processed stuff. And up your intake of veggies, but also don't be stupid and think that you'll be eating way healthier if you drown everything in ranch, cheese, or add fried chicken and stuff to salads).

Doesn't help that we're kinda fucked in that our palettes often get dictated by what we grew up on, and that health issues seem to accrue in genetics (we're more prone to certain conditions if our parents, grandparents, etc ate unhealthily; combined with what food we like tending to also follow what they liked).

@William Gaatjes are those sugar alcohols OK? i drink a bunch of them in stuff like bai5 drink

Ok? Yes and no. In moderation they should be fine, but they definitely have an affect on your gut bacteria. I eat some Protein bars (more as meal replacement than anything) and it has the sugar alcohol and says that consuming a lot of it will cause laxative effect (which you see in similar sugar free products, like the Haribo sugarfree gummy bears). I also once ate some low fat ice cream that had quite a bit of sugar alcohol in it (think it was like 5-10g per serving?), basically ate a quart in a 24 hour period and it gave me the worst (absolutely foul smelling and room filling) gas I've ever known for like 2 days straight. I used to eat some frozen yogurt that had sugar alcohol, but would eat like an ice cream cone worth a day, and never had problems.

Newer research seems to indicate that the sugar alternatives, and how they seem to not show them to be healthier than the sugar versions, wreaks havoc on our gut bacteria. I'm not sure that we fully know what is and isn't ok (some might be better than others, might affect different people with different diets differently, etc).
 

JEDIYoda

Lifer
Jul 13, 2005
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As a member of ATOT I can without reservation tell you that Jesus does NOT care!! He has more important things to worry about.........
 
May 11, 2008
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Yeah OP, and after the "HFCS is the debil!!!" bullshit, they've been trying to hide sugars under all manner of different names on the label. Which, to be fair, is ok if they're just being open about what is in their stuff and they do still have to list the amount of sugars fairly simply after all.

High amounts of sugars (in any and all forms) and refined carbs is definitely a major issue with modern diets.

Oh and sugar free soda isn't best. Research seems to indicate it has just as many issues for overall health as sugary soda, and especially might be awful on our gut bacteria.
Well, i just wanted to point out the sugar free versions of sodadrinks that have also no artificial sweeteners in it. There are some brands that sell carbonated water with a dash of lemon flavor without any sugar or sweetener in it.I did not want to make this tread about artificial sweeteners.
One subject at the time.


I'd also say you should moderate meat intake just as much as dairy. (And before the Atkins/Paleo dickheads chime in, if you're operating on a strict diet, then you could be fine if you adhere to it.)

You can't make blanket statements either. There's a lot of awful "fruit" products out there (dried fruits for instance, chocolate covered ____, etc), especially anything with juice in it. And some yogurt has tons of sugar in it (have seen a couple that have 20-30g worth, which is like 1/2 a can of pop's worth in a little yogurt cup).

Yeah i shall point out extra that i mean fresh fruit.




@William Gaatjes are those sugar alcohols OK? i drink a bunch of them in stuff like bai5 drink
Well, stuff like xorbitol (xylitol) is known to be a laxative in large quantities. So, swalloing a lot of candy and gum at once could trigger a desperate sprint to the toilet.
 

BurnItDwn

Lifer
Oct 10, 1999
26,280
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How come we are told that sugar from beets and cane is comparable, but, Mexican coke made with cane sugar is so much awesome deliciousness, and american coke made with beet sugar tastes boring?
 
May 11, 2008
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How come we are told that sugar from beets and cane is comparable, but, Mexican coke made with cane sugar is so much awesome deliciousness, and american coke made with beet sugar tastes boring?

Maybe it is not the sugar but another ingredient.
Is the Mexican coke maybe produced by crime lords that add some special ingredient. Something from the original Coca Cola 1900 recipe ?
 
May 11, 2008
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As a chemist, I can confidently tell you that they're all fucking sugar.

I am hoping you can help me out.
I do not have any chemistry background but i do have a technical background.

When fructose and glucose combine to form sucrose, it is called a dehydration reaction.
I have been drawing the little Haworth projections from wiki on paper and if i understand it correctly,
glucose has lost a hydrogen atom (H) and fructose has lost a hydroxide (HO) to combine to form sucrose. Would that lost H and HO end up as H2O (e.g. water molecule) ?
That would make sense to me because it is called a dehydration reaction.
Am i totally wrong or did i get something right ?

Does this happen spontaneously when the two monosaccharides align up to form a covalent bond ?
I know that covalent bondings can happen spontaneously but at what speed does it happen when forming sucrose ?
Is there another catalyst that is used by plants in their fruits or in chloroplasts ?


As long as there is water around, does this prevent the dehydration reaction from happening ?
The thing is that i am trying to understand, is that invertsugar spoils more easily than tablesugar (sucrose) because the monosaccharides are separate.
But glucose fructose syrup is also build up of separate monosaccharides and is advertised as having a longer shelf life than tablesugar(sucrose) and that the glucose fructose syrup in food spoils less easily.
Is there something inside the syrup that prevents spoilage ?
Is it just the water ?
I am confused.

Also, i am confused about the name isoglucose.
Isoglucose seems to translate to me as isolated glucose.
This name seems to be used for invertsugar as well for glucose fructose syrup.
Now i am totally confused because i thought these were two separate subjects.
Can you help me out understanding the chemistry and the differences between invert sugar and glucose fructose syrup ?
Both seem to have the same separate monosaccharides.


edit:
I always liked chemistry, but i never was schooled upon the subject.
 
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Genes to enzyme list :
sucrase-isomaltase is a gene coding for sucrase and isomaltase.
to be expanded...

enzymes used to digest sugars in humans :
Amylase (saliva)
Sucrase (duodenum)
Isomaltase(duodenum)
maltase(duodenum)
to be expanded...