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Discussion Eligible for a third shot, which should I get?

Geekbabe

Geekbabe

Moderator Emeritus<br>Elite Member
Cancer patient eligible for a third dose, my first two shots were Pfizer, my work is offering Moderna. I can get Pfizer but only if I Uber to a Rite Aide.
Which shot should I go for?
 
Ultimately, it probably doesn't matter much. But based on very little preliminary data, mixing seems a bit better.
www.nature.com

Mix-and-match COVID vaccines: the case is growing, but questions remain

A slew of studies suggests that mixing vaccines provokes potent immune responses, but scientists still want answers on real-world efficacy and rare side effects.
www.nature.com www.nature.com

Theoretically, the more vaccine versions you get, the better your immunity should be against upcoming variants. But, we just don't yet have much data on that.
 
From skimming over the topics here on the forums people seem to have a worse reaction to Moderna than the Pfizer shots. Just something to consider as you may need a day off.
 
I got Moderna. Day after both shots I felt pretty meh, and after the second, I had a headache, and I never get headaches. Felt fine second day after both. As always YMMV.
 
I don't think it matters a whole lot between the two mRNA shots since they're nearly identical.

Just do whichever is easiest for you. 🙂


EDIT: I would consider getting a J&J over another of the same vaccine if its an option ... I would decline any of the other vaccine-choices at the moment as a booster though. (I had Moderna originally ... far as I'm concerned it and Pfizer are equivalent)
 
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I got the M & M, no real reaction, neither melted in my hand, though there was a minor muscle ache in the upper arm.

#3 won't be due until January or so.
 
Captante said:
I don't think it matters a whole lot between the two mRNA shots since they're nearly identical.

Just do whichever is easiest for you. 🙂


EDIT: I would consider getting a J&J over another of the same vaccine if its an option ... I would decline any of the other vaccine-choices at the moment as a booster though. (I had Moderna originally ... far as I'm concerned it and Pfizer are equivalent)
Click to expand...

I just read that Moderna's durability towards delta is 76%, while Pfizer's is 42%. Not final but it's a Mayo Clinic study. They are similar, but the main difference may be volume of medicine involved. A Moderna dose is almost x3 the CCs as the Pfizer I think.

J&J booster seems very robust though.
 
kage69 said:
I just read that Moderna's durability towards delta is 76%, while Pfizer's is 42%. Not final but it's a Mayo Clinic study. They are similar, but the main difference may be volume of medicine involved. A Moderna dose is almost x3 the CCs as the Pfizer I think.

J&J booster seems very robust though.
Click to expand...
I am 2x Moderna, will be at 8 months in early Nov. since 2nd shot. I got neither through my HMO (Kaiser Permanente), but figure I am apt to get the booster through them and will get whatever they offer me, and figure it'll probably be Moderna. I figure it's probably no big deal which I get. I'd prefer one tailored to Delta and it's variants, but looks like that isn't in the cards for the original boosters.
 
I'd lean towards getting pfizer. While some data seems to show mixing is fine, unless I had no choice I'd rather not chance it personally.
 
Muse said:
News to me, I doubt it...
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The phase 1 trials for Moderna's mRNA-1010 were started in early July IIRC. It addresses 4 versions of flu: A H1N1, H3N2 and influenza B Yamagata and Victoria – all of which are recommended by the World Health Organization (WHO). So normal flu, covid19, and the HSV pair.
 
kage69 said:
The phase 1 trials for Moderna's mRNA-1010 were started in early July IIRC. It addresses 4 versions of flu: A H1N1, H3N2 and influenza B Yamagata and Victoria – all of which are recommended by the World Health Organization (WHO). So normal flu, covid19, and the HSV pair.
Click to expand...

Yeah I have heard this but it is still trials. Not the vaccine you would get now.
 
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