ECC can be helpful if you are doing critical computations or data manipulations or running RAID-0 (at a slight cost in performance). But the others are correct in that if your mobo doesn't support it, then it's a waste of money as the extra bits will just be ignored.
. Most 32-bit Athlon mobos don't support ECC. The memory controller was moved onto the CPU chip with the Athlon 64 bit CPUs (I'm not sure if that applies to ALL AMD 64-bit) so you will have to read both the AMD spec sheet on your processor and the mobo specs to be sure, but I'm fairly sure that ECC is supported at the memory controller level. For some reason, the mobo makers seldom explicitly state anything about ECC support. So also check the online FAQ and or contact tech support for your mobo.
. According to the Crucial memory configurator, ECC is supported. I also checked Asus spec sheet on that mobo and it agrees with Crucial.
.bh.