I have 4 sticks of ram, 4gb, ddr2-800, so nothing fancy at all. for voltage some people will say you can go up to 1.5v with a 65nm chip, mines at 1.4v, I wouldnt go over 1.4 if you dont wanna be drastic - I've been at this voltage for a year or so. I have my bus speed at 350mhz, with ram running 1:1 so its actually running slower than default, with nice timings. I'd say work your way up to 350mhz fsb and adjust your ram so that its not going much past its rated spec. If you have ddr2-1000 you wont need to worry so much about that. Make sure to read the sticky and download the important programs, orthos, coretemp, and especially cpuz. keep temps below 70c, volts below 1.4, ram speed not much above what its rated (400mhz for ddr2 800, 450 for 1000 give or take). Up volts on MCH by .1 if needed and on ram by .1 if needed. That should do it, pretty quick and easy and much more speed.
Theres some settings you need to disable in the motherboard settings as well, C1E for example and some others, just read the sticky though. Its just stuff that tries to save power or turn your speeds down automatically, basically stuff you would never want. I support global warming, its bloody cold.