How many time can you turn an "Etch-A-Sketch"(tm) upside-down and shake it? Chances are, HDs can withstand more write/erase cycles than one of those can. However, if improperly cooled, a HD can overheat and develop media errors during intensive operations, such as formatting or defragmenting. So keep those HDs properly cooled! Btw, defragmentation doesn't "wear out" a HD either.